Echo time optimization for J‐difference editing of glutathione at 3T

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Single Echo Time Glutamate Editing at 3 Tesla

Introduction Glutamate plays an important role in normal brain function and in brain disorders. Recently, MRS measurement of total glutamate concentration has been applied to studying several neurological and psychiatric disorders. Short-TE single voxel MRS methods cannot separate glutamate from overlapping resonances at field strengths accessible to most clinical studies. As a result, spectral...

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Multi-echo time approach for study of metabolic profiles in brain tumors at 3T

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Test-retest reliability and reproducibility of short-echo-time spectroscopic imaging of human brain at 3T.

A 1H magnetic resonance spectroscopic imaging study at 3T and short echo time was conducted to evaluate both the reproducibility, as measured by the interscan coefficient of variation (CV), and test-retest reliability, as measured by the intraclass correlation coefficient (ICC), of measurements of glutamate (Glu), combined glutamate and glutamine (Glx), myo-inositol (mI), N-acetylaspartate, cre...

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Reproducibility of phase rotation STEAM at 3T: focus on glutathione.

PURPOSE The purpose of this study was to determine the reproducibility of a very short echo time (TE) phase rotation stimulated echo acquisition mode (STEAM) sequence at 3T with a focus on the detection of glutathione. METHODS Ten healthy subjects were scanned on two separate visits. Spectra were acquired from voxels placed in the anterior and posterior cingulates. Reproducibility was assesse...

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GABA editing at 3T with Macromolecule Suppression: MEGA-SPECIAL

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2016

ISSN: 0740-3194,1522-2594

DOI: 10.1002/mrm.26122